ResusNation #89
The Freedom House Ambulance
The Freedom House Ambulance Service, operating in Pittsburgh from 1967 to 1975, was a groundbreaking initiative that transformed emergency medical care in America. Founded through a collaboration between Freedom House Enterprises, a civil rights organization, and Dr. Peter Safar (a.k.a. the "Father of CPR"), the service was created to address inadequate emergency medical care in Pittsburgh's predominantly Black Hill District neighborhood. What made it unique was its approach to recruitment – drawing paramedics from within the local community, including individuals who had faced unemployment, had criminal records, or were Vietnam War veterans.
The service implemented an unprecedented 32-week training program, featuring 300 hours of intensive medical instruction and practical experience in hospital settings. This rigorous training enabled Freedom House paramedics to provide advanced pre-hospital care that was revolutionary for its time. The service's effectiveness was quickly proven – in its first year alone, it responded to nearly 5,800 calls, transported over 4,600 patients, and saved 200 lives according to Dr. Safar's data. The program became a model for EMS systems nationwide, pioneering the first national training standards for paramedics and establishing modern ambulance design standards.
Despite its remarkable success, Freedom House faced persistent challenges due to racism and discrimination from hospital staff, patients, and local government officials. The service was ultimately terminated in 1975 when Pittsburgh's mayor established a citywide ambulance service that initially excluded most of Freedom House's Black paramedics. Nevertheless, Freedom House's legacy endures – its training standards and techniques became the foundation for modern EMS education throughout the United States, and its impact continues to influence emergency medical care today. In 2020, UPMC launched "Freedom House 2.0" to carry forward this legacy by recruiting and training first responders from underserved communities.
Welcome to the 89th edition of ResusNation!
Your Fingers Are Failing (Your Patients)
Swami and I take on pulse checks during cardiac arrest. and question why we are still using manual pulse checks in 2024. With evidence suggesting finger-based pulse checks are unreliable in cardiac arrest scenarios, he reveals how bedside ultrasound technology could revolutionize resuscitation care – not just detecting pulses, but measuring actual perfusion pressures. Find out why this emergency medicine expert thinks it's time to let go of this outdated practice and embrace modern solutions that could save more lives.
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How to Depressure-Eyes
In this episode, Dr. Shyam Murali sheds light on the fast-paced decision-making and skills required to save a patient's vision in the emergency room. Recorded live at ResusX: Reset, Dr. Murali shares insights into diagnosing and managing orbital compartment syndrome, including how to perform a lateral canthotomy to relieve intraocular pressure. This episode is essential listening for anyone in emergency medicine, offering practical tips on handling complex eye trauma and ensuring the best outcomes. Tune in for expert advice on protecting vision when every second counts!
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New Data to Drill Down?
A landmark study published in the NEJM has addressed a critical question in emergency medicine: whether intraosseous or intravenous access is more effective during out-of-hospital cardiac arrest. In this Danish trial involving nearly 1,500 patients, researchers found no significant difference in survival outcomes between the two methods, challenging current guidelines that favor intravenous access as the initial approach.
While both methods proved similarly effective regarding patient outcomes, the study revealed some interesting technical differences. Intraosseous access was successful more often on the first or second attempt compared to intravenous access (92% vs 80%), though this didn't translate to faster drug delivery or better survival rates. The researchers also compared placement sites for intraosseous access, finding that tibial placement appeared more reliable than humeral placement, with fewer technical complications.
These findings have important implications for emergency medical services. The similar effectiveness of both methods suggests that pre-hospital providers can confidently choose either approach based on their expertise and specific situation, rather than feeling compelled to attempt intravenous access first. This flexibility could be particularly valuable in challenging pre-hospital environments where multiple attempts at vascular access might delay other critical interventions. For the complete data and detailed analysis, readers are encouraged to review the full article in the New England Journal of Medicine linked here.
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A Tale of Two Antibiotics
A recent retrospective cohort study at the University of Michigan examined mortality outcomes between piperacillin-tazobactam and cefepime in sepsis patients. Using an instrumental variable analysis based on a piperacillin-tazobactam shortage, researchers found a 5% absolute increase in 90-day mortality with piperacillin-tazobactam compared to cefepime (22.5% vs 17.5%). However, this finding contrasts with the 2023 ACORN trial, which showed no mortality difference between the two antibiotics.
While the study's innovative methodology using the antibiotic shortage as an instrumental variable strengthens causal inference, several limitations warrant careful interpretation. The single-center design, potential confounding factors such as higher ICU admission rates in the piperacillin-tazobactam group (33% vs 30%), and the lack of difference in 14-day mortality suggest that other factors may influence the observed long-term mortality differences.
Key take-home messages:
The proposed mechanism involves piperacillin-tazobactam's broader anaerobic coverage potentially disrupting beneficial gut bacteria, supported by subgroup analyses showing similar mortality when anaerobic coverage was added to cefepime
• The contradiction between this study's findings and the ACORN trial, along with the absence of short-term mortality differences, suggests that longer-term outcomes may be influenced by factors beyond initial antibiotic choice
• Current practice should consider individual patient characteristics, local resistance patterns, and the need for anaerobic coverage rather than making wholesale changes based on this single retrospective study.
For a more detailed analysis and discussion of the study's implications for medical education, check out the full blog post here.
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